Autonomous vehicles and drones are transforming last-mile delivery. These technologies promise reduced labor costs, faster deliveries, and 24/7 logistics operations. As autonomy becomes more practical, the definition of supply chain management is evolving to encompass unmanned logistics systems. Companies must now consider routing algorithms, traffic regulations, maintenance protocols, and safety compliance. While still emerging, autonomous delivery is shaping future supply chain models—especially in urban and remote regions. Businesses investing in this space gain a head start on efficiency, innovation, and brand modernization. The redefined supply chain now includes fleets that think, navigate, and deliver independently.